Choose Qsymia as first-line for obesity treatment1,2

Qsymia is the only once-daily combination pill proven to significantly reduce weight.1-5

*Qsymia was studied in 2 large trials supporting FDA approval that involved 3754 patients whose BMI was 30 kg/m2 or greater, or 27 kg/m2 or greater with 2 or more weight-related comorbidities such as hypertension, type 2 diabetes mellitus, or dyslipidemia. Presented here are weight loss and waist circumference reduction in the subset of subjects (N = 2076) with a baseline BMI of 30 kg/m2 or greater, and who used study drug for the planned 56 week course of treatment. Patients were randomized to placebo, phentermine 3.75 mg/topiramate 23 mg, phentermine 7.5 mg/topiramate 46 mg, or phentermine 15 mg/topiramate 92 mg. In these trials, it was recommended that patients eat a well-balanced diet and reduce their caloric intake by 500 kcal/day. Your patients’ results may vary depending on their BMI, diet, activity, dose of Qsymia, and other factors1,2

Video: Managing Obesity as a Chronic Disease: The Role of Once-Daily Qsymia


Farhad Zangeneh, MD, FACP, FACE
Assistant Clinical Professor of Medicine
George Washington University School of Medicine
Video Length: 13:41

1.2 million Qsymia Rxs have been filled to help patients achieve their weight-loss goals1†

The only once-daily combination pill approved for chronic weight management1,3-5

  • Phentermine: Releases immediately and is thought to reduce appetite, which decreases food consumption1
  • Topiramate ER: Releases later and may help to both suppress appetite and enhance satiety1
  • The precise mechanisms of action of phentermine and topiramate ER are not known. Multiple mechanisms regulate hunger in the body—Qsymia works on multiple pathways to help your patients achieve and maintain weight loss. Qsymia is not a serotonergic agent.1,11

3.75 mg/​23 mg

The starting Qsymia dose is phentermine 3.75mg/topiramate 23mg, the pill is purple

11.25 mg/​69 mg

The titration Qsymia dose is phentermine 11.25mg/topiramate 69mg, the pill is yellow

15 mg/​92 mg

The top Qsymia dose is phentermine 15mg/topiramate 92mg, the pill is yellow and white

Please see the Important Safety Information, Full Prescribing Information and Healthcare Provider Counseling Tool for Females of Reproductive Potential.

Source: McKesson Specialty Health, 2015.

A new, special offer for your Qsymia patients

The new, Smart Changes Program is a comprehensive program that combines positive lifestyle changes with a prescription medication proven to help patients lose significant weight.

Smart Changes logo
    The Mayo Clinic Diet
Learn More

Restrictions apply. See eligibility conditions for the savings offer and the Smart Changes Program on the Qsymia patient site.

This limited free-trial offer does not represent an actual or implied endorsement of Qsymia by Mayo Clinic or The Mayo Clinic Diet. Mayo Clinic has authorized VIVUS to distribute The Mayo Clinic Diet. Mayo Clinic does not endorse any non-Mayo products or services.

Choose Qsymia as first-line choice for a range of overweight and obese patient types who need to achieve significant weight loss1,2

Qsymia has been clinically proven to provide effective and well-tolerated treatment for a range of overweight and obese patient types1-2

Review Data by Patient Type